In 2005, epidemiologist and physician John Ioannidis published the controversial and famous paper, Why Most Published Research Findings Are False in PLOS Medicine. He showed there were sound reasons to be skeptical of most published research, especially those results that rely on statistical analysis to draw conclusions about the relationship between two phenomena. Familiar examples:
• How effective is a drug?
• Does a substance in the environment increase the incidence of cancer?
• What is health effect of a food?
As he suggests, the science in most of these cases is far from settled.
By 2014, Ioannidis’s fame had grown to pop-science level. He was invited to do one of the Talks at Google, where he was given a fawning introduction by the earnest and callow member of the “People Operations Team.” He can do no wrong.... [Read More]